1D-LSD, or 1-desmethyl-D-lysergic acid diethylamide, is a novel psychedelic compound from the lysergamide family, structurally related to LSD. As a derivative of LSD, 1D-LSD shares a similar chemical structure but with some slight modifications. In this case, 1D-LSD has a desmethyl group attached, which differentiates it from traditional LSD.
Despite this modification, 1D-LSD retains many of the same pharmacological properties and subjective effects as LSD. Users report that the experience is similar to LSD, with effects that may include enhanced perception, altered thinking, and visual and auditory hallucinations.
1D-LSD is believed to primarily interact with serotonin 5-HT2A receptors in the brain, just like LSD. The chemical change may slightly alter the potency, duration, or receptor binding compared to LSD, but overall, the differences are considered minor. For those familiar with LSD, 1D-LSD provides a similar psychedelic experience with a few nuanced differences.